для лечения взрослых пациентов со всеми фазами хронического миелоидного лейкоза (ХМЛ) или острого лимфобластного лейкоза с положительной филадельфийской хромосомой (Ph+ ОЛЛ), если лечение другими ингибиторами тирозинкиназы им не подходит.

PONATINIB HYDROCHLORIDE

Iclusig is indicated in adult patients with: • chronic phase, accelerated phase, or blast phase chronic myeloid leukaemia (CML) who are resistant to dasatinib or nilotinib; who are intolerant to dasatinib or nilotinib and for whom subsequent treatment with imatinib is not clinically appropriate; or who have the T315I mutation • Philadelphia chromosome positive acute lymphoblastic leukaemia (Ph+ ALL) who are resistant to dasatinib; who are intolerant to dasatinib and for whom subsequent treatment with imatinib is not clinically appropriate; or who have the T315I mutation.